It's Mike, not understanding why Farley's impacted anal gland is a problem.
Panel 1: Lawrence notices something stuck to Farley's behind; he sniffs it, yells BLEAH in revulsion and asks Mike 'What IS that'. Mike doesn't know.
Panel 2: Lawrence holds his nose and yells "GROSS!! Get him away from me!"
Panel 3: He then yells that he's going to barf and hurl. Mike's response is to say "Lawrence....."
Panel 4: "....It's not that bad."
Panel 5: Lawrence says the only reason he's saying that is because he's at the wrong end.
Summary: Unfortunately, I do know what's wrong with Farley; either he's sick and got an impacted anal gland, he ate something he shouldn't have and the turd got stuck in his rectum or the turd is stuck to his fur; either way, this is not family-friendly material suitable for accompanying one's Egg McMuffin. It is, on the other hand, cringe-worthy material suitable for being the subject of angry letters to the editor demanding that the new-ruins be dropped.