Panel 1: We're still at the party (or, at least, a party). Joe Randomguy comes up to John and asks him how the dentist business is.
Panel 2: The
Panel 3: ...then asks John not to take offense despite his expressing hatred of all dentists everywhere.
Panel 4: John will not comply. He may hate his life but he hates being criticized even more.
Hypothesis: A man this thin-skinned would probably tend to avoid social gatherings so as to not have to deal with humor at his expense.
ETA: Since Elly is wearing a different dress, we're at a different party. My bad for not catching that.