Panel 2: Elly poses for a Virginia Slims ad, conversing with a gingerbread woman. Christopher (IIRC) is drooling and Lizzie's bottle is leaking. Yes, Elly, housework is unending. That's because people live in your house. Try prodding your husband to help out. Perhaps lower your standards a bit as well. But most importantly, stop waiting for the housework to stay done. Because that won't be possible for a long time. And by the time it does slow down, you'll have a firmly entrenched pattern of creating more work (sheet shaving) and railing at the injustice of it all (vacuuming, pets).
Panel 3: Sensible advice which Elly will find deeply insulting. And is this the first time Annie was ever drawn? This is not how I remember her looking, ever.
Panel 4: Well, isn't that sweet. Too bad we only see Elly take this attitude to be contrary.