(Original Publication Date, 16 July 1991)
Panel 1: As he walks down the aisle to find his seat, Mike tells himself "Maybe this trip will be okay. Flying to Winnipeg will be cool."
Panel 2: He then reminds us that he's a shitty older brother when he thought-bubbles about how at least he's getting away from Elizabeth and The Ape because he can only take so much from a ten year old and a baby. Since he's a turd, he probably doesn't get that they miss him just as much.
Panel 3: We set ourselves up for lunkhead irony when he says it'll be neat being on his own while checking his seat number: 21F.
Panel 4: He reacts with hostility and disbelief when he finds that his seatmates are a mother with a ten year old girl and a newborn. Since the people (who I'll call Emily, Anne and Charlotte from oldest to youngest) happen to be black, this accidentally makes Mike look racist.
Summary: We're about to be reminded that just like Elly, Mike gets along with any child he does not know personally.