Panel 2: "End of the world", not "earth". And we're reminded that Jim has a TV/comic strip affliction, not a real-world one.
Panel 3: Yep, "you and I". As in, entirely on your own.
Panel 4: Sigh, again. I wouldn't be surprised if this is the last time we see Jim, except at gatherings like Christmas and Liz's wedding. The power of love will restore Jim. Send 10 copies of this to everyone you know.