Panel 1: We set up awkwardly constructed glurge about young love with an image of 1965 Elly looking on in horror in the background as Colin and two other boys laugh themselves sick at the awkwardly constructed glurge she mistook for a passionate admission of love. Present Day Elly explains that Colin never returned her affections. What's more, he and his friends would laugh at her love notes.
Panel 2: We see her prove Marian right about being a spoiled brat when she sticks her tongue out at what's probably his yearbook photo. She proves the rest of us right about her not having the blindest idea of what love actually is when she narrates "After a while, the crush disappeared and I'd wondered why I'd ever been so crazy about him."
Panel 3: Now that they've wasted lunch listening to her natter away about a doomed crush on a boy who she stood no chance with, we see Connie putting a tip on the table as Elly explains that it amazes her that love can consume you so quickly and then go away as if it never happened; it's kind of like a sickness. Connie delivers the moral by starting to agree with that.
Panel 4: She then says that you never build up an immunity. Oddly enough, this is the only thing that's in character with the Connie of the early eighties owing to her own storied history as a desperate, fickle nitwit tossing herself at men who just weren't in to her.
Summary: Given that Mike was always hampered by the belief going in to a relationship that the person in question was laughing at him behind his back, it seems as if Lynn believes in genetic memory. Also, Elly's original belief is that what Mike is experiencing now won't last; this changes after she gets pregnant and mistakes "having to meet his parents just to be polite" with "being trapped by a schemer."