Panel 1: Yep, a dog. And of COURSE April will be allowed to watch the surgery. And maybe even assist. And probably save the dog's frikken life.
Panel 2: WHAT?! A female in Foob, being rendered unable to bear children? And is the dumbing down for April or for the reader? Anyway, why bring this up -- can't the dog just have to be wormed or something? And I love April's apprehensive expression. "What are you going to DO to this poor afflicted doggie?"
Panel 3: Oh lord, I feel a sermon coming on.
Panel 4: Okay, the whole setup was supporting the pun. What was I thinking. Laura looks like she's nudging April, and April looks like a guy. A "special needs" guy, at that. And what's the freakin' difference if you call it "fixed" or "spayed"?